Comedic action-adventure that mixes live action with cutting-edge CGI and animatronic effects. "Cats & Dogs" uncovers the truth about the high-tech, secret war being waged in neighborhoods everywhere that humans aren't even aware of: an eternal struggle between the two great armies of Cats and Dogs. The story follows a Cat plan to destroy a new vaccine that, if developed, would destroy all human allergies to Dogs, and the Dogs' efforts to stop the Cats from executing their plan.