A dozen years after exploding onto the scene with "Stay (I Missed You)" from the Gen-X movie classic Reality Bites, Lisa Loeb--one of the most recognizable musical artists of the last decade--premieres not only her first "best of" collection but her own unscripted TV series. With E! Entertainment Television's #1 Single debuting in January, The Very Best of Lisa Loeb was released January 24, 2006. Heard on both is "Single Me Out," the theme song to the TV series.

Featuring 18 selections, The Very Best of Lisa Loeb includes all of her hits from five albums from 1995 to 2004, from the orchestral "Furious Rose" to the rocking "Fools Like Me" to the stripped-down acoustic "Sandalwood," as well as the most memorable tracks from her career to date. The literary Loeb also penned the album's liner notes.

After growing up in Dallas, this modern-day Mary Tyler Moore enrolled at Brown University and formed a duo with her roommate. After graduating, she moved to New York and began playing the New York City club circuit to sell-out crowds all over downtown, backed by her group Nine Stories. Friend/fan Ethan Hawke brought her to the attention of Ben Stiller, who was starring in and directing Reality Bites. He added "Stay (I Missed You)" to the soundtrack and the single hit #1. Loeb became the first unsigned artist to ever reach the top spot. "Stay (I Missed You)" was certified gold and earned Loeb a Grammy nomination for Best Pop Performance by a Duo or Group, the U.K.'s prestigious Brit Award for Best International Newcomer, and a record deal with Geffen.

Her debut album, 1995's Tails, went gold and Top 30 and spun off the Top 20 hit "Do You Sleep?," "Waiting For Wednesday," "Taffy" and "Sandalwood." "Stay (I Missed You)" was also reprised. Known for her sexy-and-smart girl-next-door persona, accented by her trademark cat-eyed glasses, Loeb created music that touched a new generation. She toured America, opened for Lyle Lovett and appeared at the first-ever Lilith Fair, a celebration of female artists featuring Sarah McLachlan, Patti Smith, Aimee Mann, Emmylou Harris, Tori Amos and others.

1997's Grammy-nominated Firecracker yielded the Top 20 "I Do," "Truthfully," "Let's Forget About It," "Falling In Love" and "How," which debuted on the soundtrack to the summer blockbuster Twister. That year she guested on the Counting Crows' European tour and also starred at the second Lilith Fair.

From 2002's A&M album Cake and Pie, The Very Best of Lisa Loeb culls "Bring Me Up" and "Underdog." That same year a revamped indie version of the album, titled Hello Lisa, showcased "What Am I Supposed to Say." 2004's Rounder disc The Way It Really Is included "Fools Like Me."

Today, with a "best of" collection, starring in #1 Single (about looking for love in the 21st century), touring, and working on a new album, Lisa Loeb proves she is here to stay.